Nublexa tablets are supplied as generics at competitive prices. Bayer's Nublexa tablets contain regorafenib as an active ingredient. Regorafenib 40 mg is an oral multikinase inhibitor developed by Bayer that targets angiogenic, stromal and oncogenic receptor tyrosine kinase. This medicine is used to treat colon cancer.
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Use regorafenib as directed by your doctor. See the drug label for exact dosing instructions.
An additional patient leaflet comes with regorafenib. If you have questions about this information, ask your pharmacist.
Take regorafenib by mouth with water after a low-fat meal. A low-calorie meal should be less than 600 calories and less than 30% fat.
Regorafenib should be taken at the same time every day.
The tablet must be swallowed whole. Do not break, crush, or chew the tablet before swallowing.
Do not eat grapefruit or drink grapefruit juice while using regorafenib.
Regorafenib is usually taken by mouth every day for 21 days and then stopped for 7 days as directed by the doctor. This is called cyclicality. Continue to take regorafenib as directed by your doctor. Don't miss a single dose.
If you miss a dose of regorafenib, take it as soon as possible on the same day. Do not take 2 doses of the drug on the same day.
Ask your healthcare provider any questions about how to use the product.
Decreased appetite diarrhea; dry mouth; hair loss; headache; muscle rigidity; nausea; fatigue; voice changes; weakness; weight loss.
Interaction with alcohol is unknown. Please consult your doctor.
Nublexa is not safe to use during pregnancy.
There is evidence of a risk to the human fetus, but the benefits of use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Nublexa is probably not safe to use while breastfeeding. Limited data indicate that the drug may pose a significant risk to the child.
It is unknown if Nublexa alters the ability to drive. Do not drive if you have any symptoms that affect your ability to concentrate and react.
Nublexa is safe to use in patients with kidney disease. No dosage adjustment of Nublexa is recommended.
However, there is limited information on the use of Nublex tablets in patients with severe kidney disease.
Nublex tablets should be used with caution in patients with liver disease.
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